The Cochran–Armitage Trend Test (CATT) is a statistical method for detecting monotone trends in proportions across ordered categorical variables. It is especially powerful when the explanatory variable has a natural ordering and the outcome is binary.
- Clinical Trials: Testing if treatment response increases with dosage levels
- Epidemiology: Analysing disease incidence across ordered age groups
- Public Health: Examining vaccination rates across socioeconomic strata
- Genetics: Testing genotype–phenotype associations (dose-response modelling)
- Market Research: Analysing preference trends across product variants
Key assumptions: ordered categories, independent observations, binary outcome, sufficient sample size for normal approximation, non-zero marginal totals.